Business ISP Supplier Entanet UK Reveals 80Mbps Broadband ...

Communications provider Entanet, which supplies broadband internet access solutions to ISPs in the UK, has revealed how much its channel partners will have to pay if they want to offer the forthcoming 80Mbps (Megabits per second) capable Fibre-to-the-Cabinet (FTTC) based superfast broadband upgrade to their customers.

The new service, which will be available to Entanet?s clients from 12th April 2012, will apparently cost an additional ?3.25 per month (EU SSP ex VAT) when customers move from one of the existing ?up to? 40Mbps (2Mbps upload speed) packages to the 80Mbps (10Mbps uploads) option. Crucially Entanet will offer this at a special discount price of ?1.25 per month (EU SSP ex VAT) until 10th July 2012.

This means, for example, that Entanet?s resellers can offer their end user customers an ?up to? 80Mbps FTTC solution, with 15GB (GigaBytes) of inclusive monthly usage (the operators entry-level service for family packages), from ?22.83 a month (?24.83 thereafter).

Entanet?s Head of Marketing, Darren Farnden, said:

?We?ve already seen significant demand for our fibre broadband services and expect this to continue as even higher speed options emerge and availability continues to increase throughout the UK. We strive to be competitive in our pricing for this new service to enable our channel partners to compete effectively and generate profitable margins.?

It?s important to point out that this is the charge that Entanet levies against ISPs and is not necessarily what customers will pay directly. The charge, as it stands above (listed prices are Entanet?s ?end user suggested selling price?), might not include the providers full profit margin. Most other ISPs appear to be adding a consumer premium of around +?5 to +?10 inc. VAT a month for the upgrade.

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Israeli terror expert: ?Digital Pearl Harbor? worries exaggerated

While lawmakers and regulatory officials insist that the threat of a ?digital Pearl Harbor? requires the government be given more power to ward off cyber-attacks, some experts say the threat has been exaggerated.

Instead, the impending threat of ?cyber-terror? ? as one expert called it ? lies in the potential damage inflicted from the manipulation of information by the nation?s enemies, also known as information warfare.

Yael Shahar, director of Israel?s Institute for Counter-Terrorism, warned that information warfare conducted against the U.S. and American citizens, including the manipulation of financial institutions? data, was a more imminent threat than cyber-attacks against networks.

?The real threat now, the thing that worries me most of all, is not the use of cyber-tactics and cyber-weapons, and not attacks against infrastructure, and not against IT infrastructure,? Shahar told The Daily Caller.

?What worries me more is information warfare ? using information technology that?s already out there to manipulate information to make people think that they know something that they don?t know or to make people know something that isn?t true,? she added.

After being planted by hackers, such misinformation can then quickly spread around the Internet.

The digital threat to critical infrastructure like public safety or energy systems, however, is real. The STUXNET worm, one notable example, disrupted uranium enrichment processes in an Iranian nuclear facility at Nataanz.

A recent report by the Washington Post said that the Pentagon is ?accelerating efforts to develop a new generation of cyber-weapons capable of disrupting enemy military networks even when those networks are not connected to the Internet.? In 2011 the Pentagon announced that cyber-attacks against the U.S. could be considered as acts of war.

Lawmakers are worried about casualties that would result from such an attack, but examples of casualties caused by cyber-attacks are lacking.

A recent article in Foreign Policy magazine by warfare scholar Thomas Rid noted that ?there is no known cyber-attack that has caused the loss of human life.?

?No cyber-offense has ever injured a person or damaged a building,? said Rid. ?And if an act is not at least potentially violent, it?s not an act of war.?

The threat of the manipulation of economic and financial information, however, could cause severe damage to a company or government.

?For example, changing numbers in stock markets without attribution, changing foreign currency numbers in national banks, they can do a lot of damage,? said Shahar, ?but quite frankly that?s not what terrorists are after.?

Instead, countries like Russia, China, India and Iran have more of ?an interest in knowing how to manipulate information,? Shahar told TheDC.

Hacktivist group Anonymous?caused panics in the media and government by openly attacking financial institutions in 2011.?In 2010 the SEC?froze?the assets of a Russian hacker at the firm BroCo Investments, Inc. after it was suspected of manipulating the trading prices of at least 38 companies in order to financially gain from the rise and fall of the prices. In 2008, an Indian hacker ? Thirugnanam Ramanathan ? was convicted of a similar crime after he had hacked into the online trading accounts of at least 60 traders with TD Ameritrade, E*Trade, Fidelity and others, and manipulated the market prices of various financial and biotechnology companies.

Reuters reported in October 2011 that the NSA was working closely with financial institutions on Wall Street by providing intelligence on foreign hackers.

A recent report by the Washington Post said that the Pentagon is also ?accelerating efforts to develop a new generation of cyber-weapons capable of disrupting enemy military networks even when those networks are not connected to the Internet.?

?The U.S. is already thinking in terms of high-level weapons, military grade weapons, things that would bring down enemy defenses,? said Shahar. The typical response by the U.S., Shaha told TheDC, is to ?throw money at the problem.?

?Iran is more likely to be waging a homefront battle,? said Shahar. ?They?re going to be trying to influence the population to put pressure on the government. They?re not actually going to be fighting a conventional battle.?

?The U.S. is preparing for a conventional battle using cyber-methods, among others,? said Shahar. ?It?s very military-based.?

NSA Director General Keith Alexander, who is also head of the nation?s Cyber Command, said in a Senate hearing last week that he opposed the militarization of private networks.

?If we go too far, it sends the wrong message,? said Alexander.

Shahar also expressed concern about misinformation planted by hackers, which can spread through online media and social networks. Media outlets, such as news sites and blogs could be hacked, and a small piece of inaccurate information could be inserted into an article without the media outlet?s knowledge. A resulting rumor could then circulate and cause damage to a company, organization or person.

In 2011 a plan by Anonymous to attack security contractor Booze Allen Hamilton included using fake profiles to fill up various social networks with misinformation about the company, The Economist reported. Another act of misinformation used to damage a person?s reputation was the Internet rumor about former ESPN commentator Craig James, in which he allegedly killed five hookers while at SMU. The rumors, however, are false.

?I think that private citizens need to be much more aware of the possibility of manipulation,? said Shahar, ?to the point where they don?t automatically trust everything and always try to research it.?

?The problem is that people aren?t all that savvy in that sense,? said Shahar. ?They will re-circulate rumors just because it fits within their political worldview, and it?s become more of a problem now because of the echo chamber effects the Internet has produced.?

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Remember the Glomar!

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Bath Shower Screens and Glass Showers | Home Improvement ...

We live in an era of finesse, both on the professional as well as personal fronts. We make good money to live the good life and we do not compromise on our style statements, no matter how hard we have to work to attain those. One of the most impressive possessions that we own or like to show off is the home that we live in. It is for most people, one of the most cherished of dreams and it is the one thing that we work for. One of the major components inside a good home is a good bathroom. This has been proven by many people over the time and it holds credibility as well.

A bathroom is the place where you tend to spend most of your moments, major reflecting of what has been going on in the daily routine or wondering how to crack a major business deal. So it is important that your bathroom gives a certain air of comfort and also is reasonably luxurious. One of the major advances in the field of bathroom luxury is the addition of glass shower cubicles, which seem to be a rage in the world of bathroom d

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Insight: Chasing cheaper cancer drugs

LONDON | Sun Apr 1, 2012 10:19am BST

LONDON

(Reuters) - In a nondescript suburb south of London, tucked away behind a big hospital, Paul Workman and fellow scientists are celebrating victory in the "World Cup" of cancer drug research for their work in discovering a stream of new medicines.

But the win is bitter-sweet. One of the new drugs behind the coveted prize from the American Association for Cancer Research (AACR) has been deemed too costly to use in state-run British hospitals like the one next door.

It is a stark example of the pricing crisis now facing cancer medicines across the globe.

In developed and developing countries alike, patients and governments are struggling to pay for modern drugs that are revolutionizing cancer care but may cost tens of thousands of dollars a year for each patient.

"It's very frustrating," says Workman, who heads up the drug discovery unit at the Institute of Cancer Research (ICR), which is funded in large part by charities.

What is needed, he believes, is a new model that takes advantage of the highly specific nature of modern targeted therapies to slash drug development timelines and costs.

In the long term, Workman is convinced that will happen. But for the moment the world is caught in a pinch point as global drug companies put sky-high price tags on cancer medicines in a bid to recoup development costs for drugs aimed at a relatively small number of cancer sufferers.

The strains are growing - whether in Europe, where austerity has savaged healthcare budgets, or in the United States, where out-of-pocket costs can bankrupt patients, or in the developing world, where price tags of around $5,000 for a month's drug supply are simply out of reach.

INDIA LOSES PATIENCE

India, a country with a long history of making cheap off-patent drugs and a sometimes brittle relationship with Western drugmakers, has finally lost patience.

New Delhi shocked the global drugs industry in March by effectively ending Bayer's monopoly on kidney and liver cancer drug Nexavar and issuing its first-ever compulsory license, allowing local generic firm Natco Pharma to produce and sell the drug cheaply in India.

In a move to head off the same threat to its patented drugs, Roche, the world's biggest maker of cancer medicines, plans to offer significantly cheaper locally branded versions of two other cancer treatments, Herceptin and MabThera, under an alliance with Emcure Pharmaceuticals.

Further showdowns with Big Pharma seem inevitable. Novartis, for example, is challenging a decision not to grant a patent for its leukemia drug Glivec in a case that will go to the Indian Supreme Court on July 10.

Michelle Childs, head of policy at Medecins Sans Frontieres and a critic of many industry practices, says the approach taken by Big Pharma to date of excluding the vast majority of people living in developing countries - barring a small but growing middle class - is not sustainable.

She expects powerful countries like India and China, both of which have capacity to make cheap generic drugs, to flex their muscles more in future as the battle over access to medicines enters a new phase.

"Traditionally, the focus has been on drugs for infectious diseases like HIV and tuberculosis, but increasingly developing countries are facing a double burden of disease as we see the rise of chronic diseases like cancer and diabetes," she says.

The issue is not confined to poorer countries - as Workman at the ICR knows all too well.

His team spent many years working on a novel prostate cancer pill that won special recognition in the citation for the AACR prize awarded in Chicago on Sunday (April 1), only to find that Britain's National Institute for Health and Clinical Excellence (NICE) considers it too costly to be used.

If the cost-effectiveness watchdog does not change its mind, Zytiga, which is marketed by Johnson & Johnson and costs 2,930 pounds ($4,700) for a month's supply, will be off-limits for Britons on standard state healthcare.

Significantly, NICE also thinks Bayer's Nexavar is too expensive - highlighting the common concerns about costs shared by healthcare authorities in different parts of the globe.

Such tough calls are inevitable when budgets are limited, according to NICE chairman Mike Rawlins, who says it is time to challenge drug companies about the high prices they seek for products that sometimes offer only modest benefits.

$85 BLN SALES BY 2016

The debate over how to price cancer medicines matters intensely for the pharmaceuticals industry and society at large.

Cancer is a leading cause of death worldwide, accounting for 7.6 million deaths in 2008 and predicted to top 13 million in 2030, according to the World Health Organisation. Some 70 percent of deaths occur in low- and middle-income countries.

For drugmakers, the disease is a rich seam of sales and profits. Cancer medicines overtook cholesterol fighters as the biggest-selling selling prescription drug class five years ago and sales are set to hit $85 billion in 2016, up from $58 billion last year and a mere $8 billion in 2000, according to consensus forecasts compiled by Thomson Reuters Pharma.

Cancer is particularly attractive commercially as patents expire and profits wane on drugs in other areas.

Privately, though, even some drug company executives wonder if the industry will be charging such high prices in a few years time.

The price tags on a flurry of new entrants have certainly pushed the envelope, with Bristol-Myers Squibb's melanoma treatment Yervoy costing $120,000 for a four-infusion course and Dendreon's Provenge for prostate cancer priced at $93,000 for a three-dose course.

In the United States, some cancer patients have abandoned medical care because of their bills or else face a significant risk of bankruptcy, according to studies presented at the American Society of Clinical Oncology last year.

Europe's more socialized healthcare system creates different strains. Cash-strapped governments have slashed drug prices, racked up close to $20 billion in unpaid bills for treatments and, crucially, are becoming increasingly reluctant to pay for innovative new drugs.

Andrew Witty, chief executive of GlaxoSmithKline, says European governments are making a false economy by delaying the introduction and reimbursement of promising new treatments, especially for cancer, in their short-term drive to save money.

Pfizer CEO Ian Read told Reuters last month there was a serious "disconnect" between the marketplace in Europe and the desire of governments to sustain a vibrant research base. "Europe is not paying its fair share of innovation," Read said.

SMALLER, SMARTER TRIALS

From his office at the ICR behind the Marsden hospital in Sutton, Workman has an unusual vantage point across the cancer landscape. With a staff of 160, his team is as large as the oncology departments of some Big Pharma companies and in the past six years has discovered 16 innovative cancer drugs.

Thanks to rapid advances in genetics, scientists now have a fundamental understanding of the workings of tumor cells that did not exist in the days when toxic chemotherapy was the only tool in the medicine chest.

However, the lion's share of the $1 billion or more it takes to bring a new drug to market is not chewed up by scientists working in the lab but by the cost of running clinical trials. It is the high failure rate of these studies that pushes up the price of those few drugs that do succeed.

Still, there is light at the end of the tunnel. The ability to target modern cancer treatments to the genetic profile of individual patients means trials can now be designed with far fewer patients, reducing costs dramatically.

Workman predicts that in five years the average success rate for a cancer drug starting out in early-stage clinical development will be 50 percent, up from 5 percent now.

"It is no longer a lottery," he says.

"Trials in future will be smaller, quicker and cheaper. The failure rate will go down and the economic model will rebalance. That means the R&D costs that companies need to recoup when they sell a new drug will come down and those savings should be passed on to the patients."

There are already encouraging signs. Roche's new melanoma drug Zelboraf, for example, which is designed for patients with one type of abnormal gene, was approved in 2011 less than five years after the start of its first clinical trials - far shorter than the timescale for most drugs.

Even so, modern cancer drugs are never likely to be affordable to the poor of Asia, Africa and Latin America under the current patent-protected system - one reason why MSF's Childs says governments need to investigate new models for rewarding innovation, possibly via a system of upfront payments.

Back at the ICR, Workman's colleague Johann de Bono, who led much of the clinical research on Zytiga, says it is clear something in the current system has to give:

"I'm a Christian, so human life to me is very valuable. But how do you value a human life? It's very difficult." ($1 = 0.6285 British pounds)

(editing by Janet McBride)

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The Rock Will 'Crap Himself' At WrestleMania, John Cena Warns

'We're gonna see who the greatest of all time is,' Cena tells MTV News of Sunday's WM 28.
By Rob Markman, with additional reporting by Josh Horowitz


John Cena
Photo: MTV News

With the anticipation for WrestleMania XXVIII coming to a boil, you kind of get the feeling that Dwayne "The Rock" Johnson and John Cena don't really like each other. Seriously, how would you feel if the Rock called you a girl?

"He literally uses the same material over and over and over again and convinces people that it's still funny," Cena told MTV News recently, brushing the insult aside.

The two towering masses of muscle will face off on April 1 at the Sun Life Stadium in Miami Gardens, Florida, during the main event for the 28th edition of the WWE's annual WrestleMania throwdown. But the tension between the two has been building for years. In a February interview with MTV News, the Rock got personal.

"Here's the thing about John Cena: He's such a good girl, really good woman," Johnson joked. "At the end of the day, he knocked on my door, I'm gonna answer it. I've got a size-15 boot, and it's gonna go right up his stink. Or his lady parts — either one."

Cena said he's heard it all before. This Sunday, he promised, things will get serious for his opponent. "If I have lady parts, that's OK, but you're gonna pee and crap yourself at the same time when you realize you're in the ring with a professional," he said sternly.

The 6'1," 251 lb. hulk has been itching to fight the wrestler-turned-actor for seven years and now that he has his chance he doesn't plan to waste it.

"I got you man," Cena warned "The Tooth Fairy" star. "I know things about you that you don't even know about yourself," he said, addressing the Rock, who's taking a short break from Hollywood to return to the ring, directly. "April 1, we're gonna see who the greatest of all time is."

Who do you think will win the main event at WrestleMania XXVIII? Tell us in the comments!

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What earnings reports reveal about entertainment

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Source: http://news.yahoo.com/earnings-reports-reveal-entertainment-201439335.html

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Passenger detained at Philadelphia airport over fireworks

By msnbc.com news services

A small area of Philadelphia International has been reopened after a bomb squad determined a passenger was carrying fireworks in his luggage.

The 29-year-old man has been detained and is being questioned by law enforcement.

The passenger apparently forgot he was carrying the fireworks, a Philadelphia Police spokesperson said. The man never made it past security, and no flights were affected.

The man was planning to board a US Airways flight to San Francisco. The plane was not in danger, said investigators.

NBC News and?NBCPhiladelphia.com?contributed to this report.

Related stories:

Source: http://overheadbin.msnbc.msn.com/_news/2012/03/29/10919596-passenger-with-explosive-device-detained-at-philadelphia-international

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Egypt artists "reopen" street by graffiti protest

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Source: http://news.yahoo.com/egypt-artists-reopen-street-graffiti-protest-134904471.html

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Rush Soccer Group Travel ? Poll Suggests Business Travel May be ...

These have been a rough couple of years for business travelers as their companies have suffered through the recession and cut back on perks ? and in some cases, cut back on any travel at all. As FareCompare has been reporting, there are several ways for road warriors to travel on a budget ? but budgets only stretch so far.

How to Stretch Your Business Travel Budget

Business Travelers Poll

However, if a new poll is any guide, business travel is heading back to previous levels. The results of a recent online survey by the Embassy Suites chain of hotels reveal the following:

  • About 30 percent of business travelers say they?re traveling more than in 2011
  • About 32 percent still say they?re cutting back on travel (but this is down from 41 percent in 2011)
  • About 19 percent say they still cut back on meals and other expenses, but not travel itself

What Business Travelers Hate about Flying

Best and Worst Cities for Business Travel

Just over 60 percent of these business travelers also say they try to stretch out their dollars by coming business trips with leisure ? a phenomenon the Embassy chain calls bleisure travel.

Top cities for bleisure travel:

  1. San Diego
  2. Seattle
  3. Denver

Top cities business travelers would prefer to avoid (according to a different poll):

  1. Houston
  2. Los Angeles
  3. Orlando

Source: http://rushtravel.org/poll-suggests-business-travel-may-be-bouncing-back/

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Defense, DA sum up case of body in NYC high-rise

(AP) ? A handyman never did any harm to an office cleaner he's charged with smothering and stuffing into a high-rise air-conditioning vent, his lawyer said, but prosecutors called their evidence against Joseph Pabon crushing.

Both sides made closing arguments in Pabon's murder trial Thursday. Jury deliberations were expected to start Friday.

The 27-year-old Pabon is accused of killing Eridania Rodriguez, a professional bodybuilder's sister who vanished while cleaning a skyscraper in security-conscious lower Manhattan one night in July 2009. Her body was found after a four-day search.

Pabon worked in the same building. The night the 46-year-old woman disappeared, he was running a freight elevator on overtime as movers cleared furniture out of a recently vacated office.

After asking a coworker where the cleaning woman was, Pabon said he needed to use a bathroom and had someone else take over the elevator; his whereabouts weren't captured on any of the building's security cameras for the next 42 minutes, according to evidence at the trial. When he reappeared on a camera, he was in a back hallway, with a shirt around his neck.

Pabon's DNA was found on Rodriguez's fingernails and he had scratches on his neck and elsewhere. Prosecutors said he took unusual and necessary routes through the building that night to track her down and kill her on a deserted floor and then left work early, saying he was sick. An alleged motive was not part of the case against him.

The evidence "crushingly proves that the defendant is guilty beyond a reasonable doubt," Manhattan Assistant District Attorney Christine Keenan told jurors Thursday.

But Pabon's lawyers say authorities wrongly drew damning inferences from innocent circumstances and rushed to blame Pabon for a crime he didn't commit.

"That man right there didn't do a thing. Nothing," defense lawyer Mario Gallucci said in his closing argument.

Pabon barely knew Rodriguez, and he went home early because he was indeed sick, the defense says. His work involved heavy lifting that could explain the scratches on his body, and the sample of his DNA on Rodriguez's fingernails could have come from contact between the two in the course of handling a garbage bag, his lawyers say.

DNA from two other, unidentified men was found on evidence collected in the case, defense lawyers noted, and police said the building had had problems with vagrants sleeping in the stairwells.

Originally from San Francisco de Macoris in the Dominican Republic, Rodriguez had lived in Manhattan for decades. She was married with three children and had worked for about a year at the building on Rector Street, a few blocks from the World Trade Center site.

Her bodybuilder brother, Victor Martinez, is a high-ranked competitor who has won the Arnold Classic, an annual event promoted by Arnold Schwarzenegger.

Pabon, whose family is originally from Puerto Rico, had worked at the building for a few years.

___

Follow Jennifer Peltz at http://twitter.com/jennpeltz

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-03-29-Skyscraper%20Disappearance/id-fe04812d2b234715b5b9d0b717be9840

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